I don’t feel the “problems” CSS preprocessors intend to solve are serious enough to warrant the cost, i.e. to me the solution is worse than the problem.
The volume of the chorus in favor of preprocessing (I sing tenor) is so loud, I suspect it’s drowning out a decent size group of people who prefer not to use them.
In a surprise twist ending though, Roger does say he likes some forms of CSS processing, but does it directly on the source CSS itself.
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Why I don’t use CSS preprocessors is a post from CSS-Tricks